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23 results
2021
Nada Amin. 2021. “Technical Perspective: Programming Microfluidics to Execute Biological Protocols”. Commun. ACM, 64, 2, Pp. 96. doi:10.1145/3441684
Nada Amin. 2021. “Technical Perspective: Programming Microfluidics to Execute Biological Protocols”. Commun. ACM, 64, 2, Pp. 96. doi:10.1145/3441684
Jason Ott, Tyson Loveless, Chris Curtis, Mohsen Lesani, and Philip Brisk. 2021. “BioScript: Programming Safe Chemistry on Laboratories-on-a-Chip”. Commun. ACM, 64, 2, Pp. 97–104. doi:10.1145/3441686
Jason Ott, Tyson Loveless, Chris Curtis, Mohsen Lesani, and Philip Brisk. 2021. “BioScript: Programming Safe Chemistry on Laboratories-on-a-Chip”. Commun. ACM, 64, 2, Pp. 97–104. doi:10.1145/3441686
This paper introduces BioScript, a domain-specific language (DSL) for programmable biochemistry that executes on emerging microfluidic platforms. The goal of this research is to provide a simple, intuitive, and type-safe DSL that is accessible to life...
2020
Kirk Mutafopulos, Peter J. Lu, Ryan Garry, Pascal Spink, and DavidA. Weitz. 2020. “Selective Cell Encapsulation, Lysis, Pico-Injection and Size-Controlled Droplet Generation Using Traveling Surface Acoustic Waves in a Microfluidic Device”. Lab on a Chip, 21, Pp. 3914-21
Kirk Mutafopulos, Peter J. Lu, Ryan Garry, Pascal Spink, and DavidA. Weitz. 2020. “Selective Cell Encapsulation, Lysis, Pico-Injection and Size-Controlled Droplet Generation Using Traveling Surface Acoustic Waves in a Microfluidic Device”. Lab on a Chip, 21, Pp. 3914-21
We generate droplets in a microfluidic device using a traveling surface acoustic wave (TSAW), and control droplet size by adjusting TSAW power and duration. We combine droplet production and fluorescence detection to selectively-encapsulate cells and...
Ashley Stephenson, Max Willsey, Jeff McBride, Sharon Newman, Bichlien Nguyen, Christopher Takahashi, Karin Strauss, and Luis Ceze. 2020. “PurpleDrop: A Digital Microfluidics-Based Platform for Hybrid Molecular-Electronics Applications”. IEEE Micro , 40, 5, Pp. 76-86
Ashley Stephenson, Max Willsey, Jeff McBride, Sharon Newman, Bichlien Nguyen, Christopher Takahashi, Karin Strauss, and Luis Ceze. 2020. “PurpleDrop: A Digital Microfluidics-Based Platform for Hybrid Molecular-Electronics Applications”. IEEE Micro , 40, 5, Pp. 76-86
Molecular manipulation and analysis are the cornerstone of life sciences. With the recent advances in molecular data storage and computing, it has become an increasingly exciting and viable alternative for the post-CMOS scaling era. Widespread use of...
Tyson Loveless, Jason Ott, and Philip Brisk. 2020. “A Performance-Optimizing Compiler for Cyber-Physical Digital Microfluidic Biochips”. In Proceedings of the 18th ACM IEEE International Symposium on Code Generation and Optimization, Pp. 171-84
Tyson Loveless, Jason Ott, and Philip Brisk. 2020. “A Performance-Optimizing Compiler for Cyber-Physical Digital Microfluidic Biochips”. In Proceedings of the 18th ACM IEEE International Symposium on Code Generation and Optimization, Pp. 171-84
This paper introduces a compiler optimization strategy for Software-Programmable Laboratories-on-a-Chip (SP-LoCs), which miniaturize and automate a wide variety of benchtop laboratory experiments. The compiler targets a specific class of SP-LoCs that...
Jia Li, Supin Chen, and Chang-Jin Kim. 2020. “Low-Cost and Low-Topography Fabrication of Multilayer Interconnections for Microfluidic Devices ”. Journal of Micromechanics and Microengineering, 30, 7
Jia Li, Supin Chen, and Chang-Jin Kim. 2020. “Low-Cost and Low-Topography Fabrication of Multilayer Interconnections for Microfluidic Devices ”. Journal of Micromechanics and Microengineering, 30, 7
This paper report a low-cost fabrication of low-topography multilayer interconnects by selective and controlled anodization of thin-film metal layers. The process utilizes anodization of metal (tantalum in this paper) or, more specifically, repetitions of...
2019
Mohamed Ibrahim, Maria Gorlatova, and Krishnendu Chakrabarty. 2019. “The Internet of Microfluidic Things: Perspectives on System Architecture and Design Challenges”. In 2019 IEEE ACM International Conference on Computer-Aided Design (ICCAD). Westminster, CO, USA: IEEE
Mohamed Ibrahim, Maria Gorlatova, and Krishnendu Chakrabarty. 2019. “The Internet of Microfluidic Things: Perspectives on System Architecture and Design Challenges”. In 2019 IEEE ACM International Conference on Computer-Aided Design (ICCAD). Westminster, CO, USA: IEEE
The integration of microfluidics and biosensor technology is transforming microbiology research by providing new capabilities for clinical diagnostics, cancer research, and pharmacology studies. This integration enables new approaches for biochemistry...
Max Willsey, Ashley P. Stephenson, Chris Takahashi, Pranav Vaid, Bichlien H. Nguyen, Michal Piszczek, Christine Betts, Sharon Newman, Sarang Joshi, Karin Strauss, and Luis Ceze. 2019. “Puddle: A Dynamic, Error-Correcting, Full-Stack Microfluidics Platform”. In Proceedings of the Twenty-Fourth International Conference on Architectural Support for Programming Languages and Operating Systems, Pp. 183–197
Max Willsey, Ashley P. Stephenson, Chris Takahashi, Pranav Vaid, Bichlien H. Nguyen, Michal Piszczek, Christine Betts, Sharon Newman, Sarang Joshi, Karin Strauss, and Luis Ceze. 2019. “Puddle: A Dynamic, Error-Correcting, Full-Stack Microfluidics Platform”. In Proceedings of the Twenty-Fourth International Conference on Architectural Support for Programming Languages and Operating Systems, Pp. 183–197
Microfluidic devices promise to automate wetlab procedures by manipulating small chemical or biological samples. This technology comes in many varieties, all of which aim to save time, labor, and supplies by performing lab protocol steps typically done by...
2018
Jason Riordon, Dušan Sovilj, Scott Sanner, David Sinton, and Edmond W.K. Young. 2018. “Deep Learning With Microfluidics for Biotechnology”. Trends in Biotechnology, 37, 3, Pp. 310-24
Jason Riordon, Dušan Sovilj, Scott Sanner, David Sinton, and Edmond W.K. Young. 2018. “Deep Learning With Microfluidics for Biotechnology”. Trends in Biotechnology, 37, 3, Pp. 310-24
Advances in high-throughput and multiplexed microfluidics have rewarded biotechnology researchers with vast amounts of data but not necessarily the ability to analyze complex data effectively. Over the past few years, deep artificial neural networks ...
Jason Ott, Tyson Loveless, Chris Curtis, Mohsen Lesani, and Philip Brisk. 2018. “Bioscript: Programming Safe Chemistry on Laboratories-on-a-Chip”. Proceedings of the ACM on Programming Languages, 2, OOPSLA, Pp. 1-31
Jason Ott, Tyson Loveless, Chris Curtis, Mohsen Lesani, and Philip Brisk. 2018. “Bioscript: Programming Safe Chemistry on Laboratories-on-a-Chip”. Proceedings of the ACM on Programming Languages, 2, OOPSLA, Pp. 1-31
This paper introduces BioScript, a domain-specific language (DSL) for programmable biochemistry which executes on emerging microfluidic platforms. The goal of this research is to provide a simple, intuitive, and type-safe DSL that is accessible to life...
Anthony Kulesa, Jared Kehe, Juan E. Hurtado, Prianca Tawde, and Paul C. Blainey. 2018. “Combinatorial Drug Discovery in Nanoliter Droplets”. PNAS, 115, 26, Pp. 6685-90
Anthony Kulesa, Jared Kehe, Juan E. Hurtado, Prianca Tawde, and Paul C. Blainey. 2018. “Combinatorial Drug Discovery in Nanoliter Droplets”. PNAS, 115, 26, Pp. 6685-90
2016
Ehsan Samiei, Maryam Tabrizian, and Mina Hoorfar. 2016. “A Review of Digital Microfluidics As Portable Platforms for Lab-on A-Chip Applications”. Lab on a Chip, 16, 13, Pp. 2376-96
Ehsan Samiei, Maryam Tabrizian, and Mina Hoorfar. 2016. “A Review of Digital Microfluidics As Portable Platforms for Lab-on A-Chip Applications”. Lab on a Chip, 16, 13, Pp. 2376-96
Following the development of microfluidic systems, there has been a high tendency towards developing lab-on-a-chip devices for biochemical applications. A great deal of effort has been devoted to improve and advance these devices with the goal of...